Have you tried MySQLTuner yet? It's free and it makes optimizing your MySQL server easier than ever!

If you find that someone has done a recursive chmod or chown on a server, don’t fret. You can set almost everything back to its original permissions and ownership by doing the following:

rpm -qa | xargs rpm --setperms --setugids

Depending on how many packages are installed as well as the speed of your disk I/O, this may take a while to complete.

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